Osteomyelitis and Septic Arthritis in the Darwin Prospective Melioidosis Study.

ABSTRACT:

Background

Melioidosis is a multisystem infectious disease caused by the environmental bacterium Burkholderia pseudomallei. Osteomyelitis (OM) and septic arthritis (SA) are uncommon primary presentations for melioidosis but important secondary foci, often requiring prolonged therapy and multiple surgeries. We characterized the epidemiology, presentation, treatment, and outcomes of patients from 24 years of the Darwin Prospective Melioidosis Study (DPMS).

Methods

DPMS patients from October 1, 1999, until September 30, 2023, were included if they had a primary or secondary diagnosis of OM or SA. Epidemiological, risk factor, clinical, and outcome data were retrieved from the DPMS database. Antibiotic and surgical data were collated from patient records.

Results

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SUBMITTER: Campbell S 

PROVIDER: S-EPMC11697087 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature