<i>Streptococcus pneumoniae</i> Serotype Distribution Among US Adults Hospitalized With Community-Acquired Pneumonia, 2019-2020.

ABSTRACT:

Background

Serotype-specific urinary antigen detection (UAD) assay results can be used to estimate the serotype contribution among adults with pneumococcal community-acquired pneumonia (CAP) and to guide recommendations regarding higher-valency pneumococcal conjugate vaccines (PCVs).

Methods

Adults aged ≥18 years hospitalized with radiographic evidence of CAP were prospectively enrolled in 4 US cities from November 2019 to December 2020, overlapping the coronavirus disease 2019 (COVID-19) pandemic. Data were collected by patient interview and medical chart review. Streptococcus pneumoniae was isolated from standard-of-care respiratory samples and blood; urine collected per-protocol was tested by S pneumoniae BinaxNOW and UAD assays. The proportions of adults wi

SUBMITTER: Ramirez JA 

PROVIDER: S-EPMC11697090 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature