The anticancer activity of fucoidan coated selenium nanoparticles and curcumin nanoparticles against colorectal cancer lines.

ABSTRACT: Cancers still globally endanger millions of people yearly; the incidences/mortalities of colorectal cancers are particularly increasing. The natural nanoparticles (NPs) and marine biopolymers were anticipated to provide effectual safe significances for managing cancers. The transformation of curcumin to nano-curcumin (NCur) was conducted with gum Arabic. The resulted NCur was utilized for the biosynthesis of selenium NPs (SeNPs), then bioactive nanocomposites (NC) from them with fucoidan (Fu) were fabricated and evaluated as candidates to suppress colorectal cancers (CaCo-2 and HT-29) cells. The NCur and NCur-synthesized SeNPs were effectually produced with mean diameters of 34.67 ± 4.32 and 5.17 ± 1.06 nm, respectively. The plain and NCs of Fu/NCur/SeNPs characterization, with infrared sp

SUBMITTER: Al-Duais MA 

PROVIDER: S-EPMC11697394 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature