Dimensions of childhood adversity differentially affect autonomic nervous system coordination in response to stress.

ABSTRACT: It is well-established that disrupted autonomic nervous system (ANS) reactivity exacerbates risk for long-term maladjustment following childhood adversity (CA). However, few studies have integrated measures of both the sympathetic (SNS) and parasympathetic (PNS) branches of the ANS, resulting in a unidimensional understanding of ANS functioning as a mechanism of risk. Further, past work has primarily measured CA only at the aggregate level (e.g. "total CA"), necessitating further research to accurately characterize this risk pathway. The present study examines how CA, measured cumulatively and dimensionally (i.e. CA characterized by threat versus deprivation), moderates the association between the SNS and PNS at rest and in response to acute social and nonsocial stressors. Participants inc

SUBMITTER: Gruhn MA 

PROVIDER: S-EPMC11697412 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature