Modeling COVID-19 dynamics in the Basque Country: characterizing population immunity profile from 2020 to 2022.

ABSTRACT:

Background

COVID-19, caused by SARS-CoV-2, has spread globally, presenting a significant public health challenge. Vaccination has played a critical role in reducing severe disease and deaths. However, the waning of immunity after vaccination and the emergence of immune-escape variants require the continuation of vaccination efforts, including booster doses, to maintain population immunity. This study models the dynamics of COVID-19 in the Basque Country, Spain, aiming to characterize the population's immunity profile and assess its impact on the severity of outbreaks from 2020 to 2022.

Methods

A SIR/DS model was developed to analyze the interplay of virus-specific and vaccine-induced immunity. The model includes three levels of immunity, with boosting effects from reinfectio

SUBMITTER: Naffeti B 

PROVIDER: S-EPMC11697651 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature