Clinical presentation and predictors of hospital mortality of diphtheria in Nigeria, July 2023 to April 2024: a single-center study.

ABSTRACT:

Background

Despite recurrent outbreaks of diphtheria in Nigeria, there is a lack of in-depth analysis of hospitalization outcomes. Herein, we describe the sociodemographic, clinical, and laboratory features associated with hospitalization outcomes (defined as death or discharge) during the recent diphtheria outbreak in Nigeria.

Methods

This prospective observational study included 246 confirmed diphtheria cases managed in a dedicated isolation ward of a health facility in northwestern Nigeria from July 1, 2023, to April 30, 2024. We analyzed clinical and laboratory features, immunization status, and socio-demographics in relation to hospitalization deaths using SPSS version 29.

Results

The median age (interquartile range) was 7.00 (4-10) years and 49.6% (122) were age

SUBMITTER: Alege A 

PROVIDER: S-EPMC11697654 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature