Cognitive, adaptive and daily life functioning in adults with 22q11.2 deletion syndrome.

ABSTRACT:

Background

22q11.2 deletion syndrome (22q11.2DS) is associated with cognitive impairments and an increased risk of psychopathology. Most of the research has been conducted in children and adolescents, although the majority of affected individuals live well into adulthood. Hence, limited data are available on functional outcomes in adults.

Aims

To provide more insight in cognitive and adaptive abilities, and daily life functioning (marital status, living situation and work situation) in adults with 22q11.2DS.

Method

This retrospective study included 250 Dutch-speaking adults (16-69 years) with 22q11.2DS from three sites in The Netherlands and Belgium. Data on full-scale IQ (FSIQ) scores (assessed with the Wechsler Adult Intelligence Scale), adaptive functioning (assess

SUBMITTER: Vingerhoets C 

PROVIDER: S-EPMC11698185 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature