Externally validated clinical prediction models for estimating treatment outcomes for patients with a mood, anxiety or psychotic disorder: systematic review and meta-analysis.

ABSTRACT:

Background

Suboptimal treatment outcomes contribute to the high disease burden of mood, anxiety or psychotic disorders. Clinical prediction models could optimise treatment allocation, which may result in better outcomes. Whereas ample research on prediction models is performed, model performance in other clinical contexts (i.e. external validation) is rarely examined. This gap hampers generalisability and as such implementation in clinical practice.

Aims

Systematically appraise studies on externally validated clinical prediction models for estimated treatment outcomes for mood, anxiety and psychotic disorders by (1) reviewing methodological quality and applicability of studies and (2) investigating how model properties relate to differences in model performance.

Method

SUBMITTER: Burghoorn DG 

PROVIDER: S-EPMC11698186 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature