Relationship between oxidative balance indicators and Chronic Kidney Disease.

ABSTRACT:

Introduction

Chronic Kidney Disease (CKD) is a growing global health issue, affecting approximately 9.1% of the world's population. Oxidative stress is believed to play a key role in CKD development, with indicators such as the Oxidative Balance Score (OBS), Pro-Oxidant-Antioxidant Balance (PAB), and Total Antioxidant Capacity (TAC) being of particular interest. However, their association with CKD remains unclear.

Methods

This study conducted a cross-sectional analysis using data from the National Health and Nutrition Examination Survey (NHANES) 2009-2018. A total of 18,951 participants were included after applying specific inclusion criteria. Logistic regression models and restricted cubic spline regression were employed to examine the associations between these oxidative b

SUBMITTER: Chen X 

PROVIDER: S-EPMC11698424 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature