Intravenous thrombolysis in patients with acute dizziness or imbalance and suspected ischemic stroke-systematic review.

ABSTRACT:

Background

Correct identification of those patients presenting with an acute vestibular syndrome (AVS) or an acute imbalance syndrome (AIS) that have underlying posterior-circulation stroke (PCS) and thus may benefit from revascularization (intravenous thrombolysis (IVT), endovascular therapy (EVT)) is important. Treatment guidelines for AVS/AIS patients are lacking. We reviewed the evidence on acute treatment strategies in AVS/AIS focusing on predictors for IVT/EVT and outcome.

Methods

We performed a systematic search (MEDLINE, Embase) to identify studies reporting on acute treatment in PCS presenting as AVS/AIS (PROSPERO-registration = CRD42024537272). Key parameters were extracted. Risk of bias was assessed (Downs-and-Black quality assessment checklist).

Results

We

SUBMITTER: Edlow JA 

PROVIDER: S-EPMC11698810 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature