Genetic diversity of Plasmodium vivax and Plasmodium falciparum field isolates from Honduras in the malaria elimination phase.

ABSTRACT: Malaria continues to be a major threat to public health in tropical regions, primarily affecting sub-Saharan Africa but also Asia, the Middle East, and Latin America. Malaria cases in Honduras have seen a significant decline and the country aims to eliminate the disease by 2030. This study examines the genetic diversity of Plasmodium falciparum and Plasmodium vivax in Honduras using four molecular markers (Pfama1, Pfglurp, Pvmsp3α, and Pvmsp3β), and the chloroquine resistance marker pfcrt in the context of the elimination phase. Our findings indicate that P. falciparum populations in Honduras are more homogeneous compared to P. vivax. The multilocus sequence typing (MLST) approach, using four loci from Pvmsp3α and Pvm

SUBMITTER: Zamora A 

PROVIDER: S-EPMC11699087 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature