Epidemiological and genetic charateristics of Vibrio vulnificus from diverse sources in China during 2012-2023.

ABSTRACT: Vibrio vulnificus is a significant zoonotic pathogen that causes severe vibriosis in humans and fish. The lack of a national annual surveillance program in China has hindered understanding of its epidemiological characteristics and genetic diversity. This study characterized 150 V. vulnificus isolates collected from diverse sources in China during 2012-2023, including seafood, aquaculture water, migratory birds, marine animals, and clinical patients. Most seafood-derived isolates and all 15 clinical isolates harbored the virulence-related gene vcgC and 16S rRNA type B. The isolates exhibited diverse virulence factors (VFs), including flagella, outer membrane components, RTX toxins, and multiple secretion systems. Genes associated with the Type III secretion system were identified in migrat

SUBMITTER: Long D 

PROVIDER: S-EPMC11700198 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature