Impact of deep brain stimulation on gait in Parkinson disease: A kinematic study.

ABSTRACT:

Background

The effect of Deep Brain Stimulation (DBS) on gait in Parkinson's Disease (PD) is poorly understood. Kinematic studies utilizing quantitative gait outcomes such as speed, cadence, and stride length have shown mixed results and were done mostly before and after acute DBS discontinuation.

Objective

To examine longitudinal changes in kinematic gait outcomes before and after DBS surgery.

Method

We retrospectively assessed changes in quantitative gait outcomes via motion capture in 22 PD patients before and after subthalamic (STN) or globus pallidus internus (GPi) DBS, in on medication state. Associations between gait outcomes and clinical variables were also assessed.

Result

Gait speed reduced from 110.7 ± 21.3 cm/s before surgery to 93.6 ± 24.9 after su

SUBMITTER: Tripathi R 

PROVIDER: S-EPMC11700382 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature