Determinants of persistence and recovery of chronic coronavirus disease 2019 chemosensory dysfunction.

ABSTRACT:

Background

In 2% to 4% of patients, coronavirus disease 2019 (COVID-19) chemosensory dysfunction (CSD) persists beyond 6 months, accounting for up to 4 million people in the United States. The predictors of persistence and recovery require further exploration.

Objective

We sought to define the predictors of recovery and assess the quality of CSD in registry subjects with self-reported persistent smell and taste dysfunction after COVID-19.

Methods

COVID-19 CSD participants (n = 408) from the 4 major waves of the pandemic completed questionnaires at 4 time points between 2021 and 2023, assessing demographics, sinonasal symptoms, and self-assessed recovery. Objective measurements of smell (UPSIT) and taste (BWETT) were performed on a subcohort (n = 108).

Results

I

SUBMITTER: Minichetti DG 

PROVIDER: S-EPMC11700771 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature