ABSTRACT: Oil palm (Elaeis guineensis) yield is impacted by abiotic stresses, leading to significant economic losses. To understand the core abiotic stress transcriptome (CAST) of oil palm, we performed RNA-Seq analyses of oil palm leaves subjected to drought, salinity, waterlogging, heat, and cold stresses. A total of 19,834 differentially expressed genes (DEGs) were identified. Cold treatment induced the highest number of DEGs (5,300), followed by heat (4,114), drought (3,751), waterlogging (3,573), and, lastly, salinity (3096) stress. Subsequent analysis revealed the CAST of oil palm, comprising 588 DEGs commonly expressed under drought, salinity, waterlogging, heat, and cold stress conditions. Function annotation of these DEGs suggests their roles in signal transduction, transcription reg