DbAMP 3.0: updated resource of antimicrobial activity and structural annotation of peptides in the post-pandemic era.

ABSTRACT: Antimicrobial resistance is one of the most urgent global health threats, especially in the post-pandemic era. Antimicrobial peptides (AMPs) offer a promising alternative to traditional antibiotics, driving growing interest in recent years. dbAMP is a comprehensive database offering extensive annotations on AMPs, including sequence information, functional activity data, physicochemical properties and structural annotations. In this update, dbAMP has curated data from over 5200 publications, encompassing 33,065 AMPs and 2453 antimicrobial proteins from 3534 organisms. Additionally, dbAMP utilizes ESMFold to determine the three-dimensional structures of AMPs, providing over 30,000 structural annotations that facilitate structure-based functional insights for clinical drug development. Furthe

SUBMITTER: Yao L 

PROVIDER: S-EPMC11701527 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature