ScCancerExplorer: a comprehensive database for interactively exploring single-cell multi-omics data of human pan-cancer.

ABSTRACT: Genomic, epigenomic and transcriptomic alterations are hallmarks of cancer cells, and are closely connected. Especially, epigenetic regulation plays a critical role in tumorigenesis and progression. The growing single-cell epigenome data in cancer research provide new opportunities for data mining from a more comprehensive perspective. However, there is still a lack of databases designed for interactively exploring the single-cell multi-omics data of human pan-cancer, especially for the single-cell epigenome data. To fill in the gap, we developed scCancerExplorer, a comprehensive and user-friendly database to facilitate the exploration of the single-cell genome, epigenome (chromatin accessibility and DNA methylation), and transcriptome data of 50 cancer types. Five major modules were provi

SUBMITTER: Huang C 

PROVIDER: S-EPMC11701644 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature