The association between urine neutrophil gelatinase-associated lipocalin and UTI in people with neurogenic lower urinary tract dysfunction.

ABSTRACT:

Study design

Secondary analysis of urine samples collected from a prospective within-subject clinical trial.

Objectives

Describe the baseline variation in urine neutrophil gelatinase-associated lipocalin (uNGAL) levels in adults with neurogenic lower urinary tract dysfunction (NLUTD) and determine if uNGAL levels vary according to likelihood of having a UTI.

Setting

Greater Washington D.C. region.

Methods

Urine samples were collected from a cohort of adults with NLUTD from a clinical trial. Samples were divided into groups of "Not UTI", "Unlikely UTI", and "Likely UTI" based on symptoms and urine culture results. uNGAL was compared between groups using Kruskal-Wallis and post hoc Dunn's test. Mixed effects logistic model was used to assess the association of uN

SUBMITTER: Forster CS 

PROVIDER: S-EPMC11702270 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature