Airborne transmission efficiency of SARS-CoV-2 in Syrian hamsters is not influenced by environmental conditions.

ABSTRACT: Several human respiratory viruses display a clear seasonal pattern with a higher incidence in the winter season in temperate regions. We previously determined that SARS-CoV-2 is more stable at low-temperature and low-humidity conditions compared to warmer temperature and higher-humidity. To determine if this translates into differential airborne transmission rates in vivo, we performed airborne transmission experiments in the Syrian hamster model under three different environmental conditions (10 °C, 45% relative humidity (RH), 22 °C, 45% RH, and 27 °C, 65% RH). We compared the ancestral SARS-CoV-2 Lineage A with the more transmissible Delta Variant of Concern (VOC). Airborne transmission was evaluated using SARS-CoV-2 infected donor animals at 24 h post inoculation. Sentinels were placed

SUBMITTER: Yinda CK 

PROVIDER: S-EPMC11702665 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature