Advantages to interspace-level analyses over person-level analyses when studying relationships between lumbar spinal degeneration findings : a cross-sectional study.

ABSTRACT:

Purpose

To examine associations between lumbar intervertebral disc degeneration (LDD) and type II Modic changes (MC) when retaining information at each interspace ("interspace-level analysis"), as compared to aggregating information across interspaces as is typically done in spine research ("person-level analysis") . The study compared results from (1) interspace-level analyses assuming a common relationship across interspaces (the "interspace-level, common-relationship" approach), (2) interspace-level analyses allowing for interspace-specific associations (an "interspace-level, interspace-specific" approach), and (3) a conventional person-level analytic approach.

Methods

Adults in primary care (n=147) received lumbar spine magnetic resonance imaging (MRI) and neuroradiologi

SUBMITTER: Suri P 

PROVIDER: S-EPMC11703305 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature