Cryoneurolysis for phantom limb pain: a systematic review.

ABSTRACT:

Aims

Phantom limb pain (PLP) is a painful sensation occurring in patients around the site of an amputation. The aim of this systematic review is to evaluate the efficacy of cryoneurolysis in the management of phantom limb pain.

Materials and methods

A systematic review was performed according to the PRISMA 2020 guidelines. An initial search yielded 200 articles from four major scientific databases (PubMed, Embase, Cochrane Library, WebOfScience). Five articles met inclusion criteria, four of which underwent additional pooled statistical analysis.

Results

Pooled analysis of the included trials revealed a cumulative Cohen's d effect size of 1.55 (95% CI [0.24, 2.87]; p = 0.02; z = 2.32) for the reduction of pain on a 10-point pain scale following cryoneurolysis i

SUBMITTER: Brancaccio H 

PROVIDER: S-EPMC11703452 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature