Estrogen sulfotransferase SULT1E1 expression correlates with progression and prognosis of lung adenocarcinoma.

ABSTRACT: Estrogen sulfotransferase (SULT1E1), a member of the sulfotransferase family (SULTs), is the enzyme with the strongest affinity for estrogen. Despite significant associations between SULT1E1 and the progression and prognosis of a range of diseases, its functional role and potential mechanisms in lung adenocarcinoma (LUAD) remain unclear. The objective of this study was to examine the potential of SULT1E1 as a biomarker for LUAD. The molecular characteristics, disease relevance and expression levels of SULT1E1 in different cancers were analysed using public databases. GEPIA 2, Starbase and other databases were employed to analyse the expression levels of SULT1E1 in LUAD tissues and normal lung tissues, and to investigate the correlation with clinical stages. A prognostic analysis was conduc

SUBMITTER: Wang R 

PROVIDER: S-EPMC11704053 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature