Acoustic-based rule-out of stable coronary artery disease: the FILTER-SCAD trial.

ABSTRACT:

Background and aims

Overtesting of low-risk patients with suspect chronic coronary syndrome (CCS) is widespread. The acoustic-based coronary artery disease (CAD)-score has superior rule-out capabilities when added to pre-test probability (PTP). FILTER-SCAD tested whether providing a CAD-score and PTP to cardiologists was superior to PTP alone in limiting testing.

Methods

At six Danish and Swedish outpatient clinics, patients with suspected new-onset CCS were randomized to either standard diagnostic examination (SDE) with PTP, or SDE plus CAD-score, and cardiologists provided with corresponding recommended diagnostic flowcharts. The primary endpoint was cumulative number of diagnostic tests at one year and key safety endpoint major adverse cardiac events (MACE).

Results

SUBMITTER: Bjerking LH 

PROVIDER: S-EPMC11704391 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature