Identifying fecal microbiota signatures of colorectal cancer in a Vietnamese cohort.

ABSTRACT:

Background

Colorectal cancer (CRC) is among the top three causes of global cancer mortality. In Vietnam, CRC is the third leading cause of death in women and the fourth cause of cancer mortality in men. A large number of metagenomic studies have reported the relationship between altered composition and function of the gut microbiota with CRC, but this relationship in low- and middle-income countries including Vietnam (with an estimated population of 100.3 million people in 2023, ranking 16th largest country by population in the world) is not well-explored.

Methods

We collected clinical data and fecal samples from 43 CRC patients and 44 healthy control subjects. The total community DNA of microorganisms was extracted from the fecal samples and analyzed for microbiota composit

SUBMITTER: Nhung PTT 

PROVIDER: S-EPMC11704495 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature