Extracellular vesicle-mediated approaches for the diagnosis and therapy of MASLD: current advances and future prospective.

ABSTRACT: Metabolic dysfunction-associated steatotic liver disease (MASLD) is an asymptomatic, multifaceted condition often associated with various risk factors, including fatigue, obesity, insulin resistance, metabolic syndrome, and sleep apnea. The increasing burden of MASLD underscores the critical need for early diagnosis and effective therapies. Owing to the lack of efficient therapies for MASLD, early diagnosis is crucial. Consequently, noninvasive biomarkers and imaging techniques are essential for analyzing disease risk and play a pivotal role in the global diagnostic process. The use of extracellular vesicles has emerged as promising for early diagnosis and therapy of various liver ailments. Herein, a comprehensive summary of the current diagnostic modalities for MASLD is presented, highlig

SUBMITTER: Gurjar S 

PROVIDER: S-EPMC11705780 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature