Differential vasoproliferative traits of Bartonella henselae strains associated with autotransporter BafA variants.

ABSTRACT: Bartonella henselae, a Gram-negative facultative intracellular bacterium, is the etiological agent of cat-scratch disease and also causes bacillary angiomatosis in immunocompromised individuals. Although the ability to promote vascular endothelial cell proliferation differs among Bartonella species, variations among strains within B. henselae remain unclear. Bartonella angiogenic factor A (BafA) and Bartonella adhesin A (BadA) have been identified as autotransporters of B. henselae that are involved in endothelial cell proliferation. Although strain-specific differences in the expression of BadA and the VirB/D4 type IV secretion system have been reported, BafA expression among B. henselae strains has yet to be examined. Therefore, the presen

SUBMITTER: Kondo Y 

PROVIDER: S-EPMC11705867 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature