Antimicrobial resistance, virulence gene profiles, and molecular epidemiology of enterococcal isolates from patients with urinary tract infections in Shanghai, China.

ABSTRACT: Urinary tract infections (UTIs) are among the most prevalent infectious diseases, yet there is still limited understanding of the epidemiology of Enterococcal strains isolated from UTI patients in Shanghai. This study aims to elucidate the antimicrobial resistance profiles, virulence gene carriage, and molecular epidemiology of selected Enterococcal strains from UTI patients in Shanghai. A cohort of 80 Enterococcus faecalis and 40 Enterococcus faecium clinical isolates were randomly selected from UTI patients from October 2022 to March 2023. No vancomycin-resistant strains were identified based on minimum inhibitory concentration (MIC) testing. However, five strains of linezolid-resistant E. faecalis were identified, all of which were confirmed to be optrA-posit

SUBMITTER: Wu W 

PROVIDER: S-EPMC11705914 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature