Linear Plasmids in Micrococcus: Insights Into a Common Ancestor and Transfer by Conjugation.

ABSTRACT: Actinobacteria have frequently been reported in the Andean Puna, including strains of the genus Micrococcus. These strains demonstrate resistance to high levels of UV radiation, arsenic, and multiple antibiotics, and possess large linear plasmids. A comparative analysis of the sequences and putative functions of these plasmids was conducted. The presence of large regions with high sequence identity (exceeding 30 kb in total) in all three studied Micrococcus megaplasmids indicates a clear evolutionary link among these elements. Genes related to essential plasmid functions were primarily found within these conserved regions, while genes associated with resistance to metals and antibiotics resided in accessory regions. Moreover, the abundance of open reading frames related to transposition an

SUBMITTER: Perez MF 

PROVIDER: S-EPMC11707576 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature