Engaging a highly fluorescent conjugated polymer network for probing endogenous hypochlorite in macrophage cells: improved sensitivity <i>via</i> signal amplification.

ABSTRACT: We have employed a triazine-based conjugated polymer network (CPN) for the selective detection of hypochlorite in a semi-aqueous environment. CPNs have been widely employed in gas capture, separation, and adsorption, but the fluorescent properties of CPNs possessing extensive π-conjugated systems tend to be unexplored. Herein, we report the photophysical properties of the CPN and investigate its sensing capability towards hypochlorite. Spectroscopic investigations reveal that the CPN forms π-stacked aggregates in aqueous medium, while loose aggregates were observed to be formed in hydrophobic solvents. The fluorogenic CPN demonstrates remarkable selectivity via fluorescence quenching and a blueshift response towards hypochlorite in a semi-aqueous medium, accompanied by a color chang

SUBMITTER: Fernandes RS 

PROVIDER: S-EPMC11708206 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature