Chromosome-level echidna genome illuminates evolution of multiple sex chromosome system in monotremes.

ABSTRACT:

Background

A thorough analysis of genome evolution is fundamental for biodiversity understanding. The iconic monotremes (platypus and echidna) feature extraordinary biology. However, they also exhibit rearrangements in several chromosomes, especially in the sex chromosome chain. Therefore, the lack of a chromosome-level echidna genome has limited insights into genome evolution in monotremes, in particular the multiple sex chromosomes complex.

Results

Here, we present a new long reads-based chromosome-level short-beaked echidna (Tachyglossus aculeatus) genome, which allowed the inference of chromosomal rearrangements in the monotreme ancestor (2n = 64) and each extant species. Analysis of the more complete sex chromosomes uncovered homology between 1 Y chromosome and multiple

SUBMITTER: Zhou Y 

PROVIDER: S-EPMC11710854 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature