Residual Fatigue in Unipolar and Bipolar Depression: A Systematic Review.

ABSTRACT:

Background

Residual fatigue is a common and debilitating symptom in patients with unipolar and bipolar depression, even after achieving partial or full remission. It significantly impacts patients' quality of life and increases the risk of relapse. This systematic review aims to evaluate the prevalence and effectiveness of therapeutic options for residual fatigue in individuals with unipolar major depressive disorder (MDD) and bipolar disorder (BD).

Methods

A comprehensive search was conducted in the PubMed, SCOPUS, and Web of Science databases up to September 2024. The protocol for this systematic review was registered in PROSPERO. The search strategy included terms related to depression and residual fatigue. Studies were included if they provided data on adult patients dia

SUBMITTER: Pastuszak M 

PROVIDER: S-EPMC11713126 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature