Statin therapy in ischemic stroke patients with atrial fibrillation: Efficacy and safety outcomes.

ABSTRACT:

Introduction

The efficacy and safety of statins for secondary prevention in patients who have experienced a cardioembolic stroke are not well-defined. However, previous observational data reported hyperlipidemia as a risk factor for both ischemic and bleeding complications in patients with AF and previous stroke. Based on these premises, we conducted a sub-analysis of the RAF and RAF-NOAC studies to evaluate the efficacy and safety of statins in secondary prevention in patients with acute ischemic stroke and AF.

Materials and methods

We combined patient data from the RAF and RAF-NOAC studies, prospective observational studies conducted across Stroke Units in Europe, the United States, and Asia from January 2012 to June 2016. We included consecutive patients with AF who suffe

SUBMITTER: Marvardi M 

PROVIDER: S-EPMC11713940 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature