Do the gait domains change in PD patients with freezing of gait during their 'interictal' period?

ABSTRACT:

Objectives

Freezing of Gait (FOG) is one of the disabling symptoms in patients with Parkinson's Disease (PD). While it is difficult to early detect because of the sporadic occurrence of initial freezing events. Whether the characteristic of gait impairments in PD patients with FOG during the 'interictal' period is different from that in non-FOG patients is still unclear.

Methods

The gait parameters were measured by wearable inertial sensors. Exploratory factor analysis was used to investigate the inherent structure of diverse univariate gait parameters, with the aim of identifying shared characteristics among the gait variables.

Results

This cross-sectional study involved 68 controls and 245 PD patients (167 without FOG and 78 with FOG). The analysis yielded six disti

SUBMITTER: Zhao J 

PROVIDER: S-EPMC11715180 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature