Sex differences in tuberculosis infection and disease among people with HIV.

ABSTRACT:

Objectives

Worldwide, adult men experience an excess burden of tuberculosis (TB) disease compared with women, but few studies have examined sex differences in TB among people with HIV. In this study, we aimed to investigate sex differences in TB infection and disease among people with HIV in Rio de Janeiro, Brazil.

Design

Analysis of data from a randomized controlled trial and retrospective cohort study.

Methods

We analyzed data from two studies conducted between 2005 and 2017. The THRio Study (2005-2012) evaluated increasing tuberculin skin testing (TST) and TB preventive therapy (TPT), and Universal ART in Rio study (UnivART; 2010-2017) was a virtual cohort study of people with HIV and TB with data from four national electronic registries.

Results

Among 4606

SUBMITTER: Chaisson LH 

PROVIDER: S-EPMC11717608 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature