Affective Visual Circuit Dysfunction in Trauma and Stress-Related Disorders.

ABSTRACT: Posttraumatic stress disorder (PTSD) is widely recognized as involving disruption of core neurocircuitry that underlies processing, regulation, and response to threat. In particular, the prefrontal cortex-hippocampal-amygdala circuit is a major contributor to posttraumatic dysfunction. However, the functioning of core threat neurocircuitry is partially dependent on sensorial inputs, and previous research has demonstrated that dense, reciprocal connections exist between threat circuits and the ventral visual stream. Furthermore, emergent evidence suggests that trauma exposure and resultant PTSD symptoms are associated with altered structure and function of the ventral visual stream. In the current review, we discuss evidence that both threat and visual circuitry together are an integral par

SUBMITTER: Harnett NG 

PROVIDER: S-EPMC11717988 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature