Organ-specific malperfusion in acute type A aortic dissection: epidemiological meta-analysis of incidence rates.

ABSTRACT:

Background

Acute type A aortic dissection is a life-threatening clinical emergency that necessitates immediate surgical intervention with an estimated mortality rate of approximately 1-2% per hour. When complicated by malperfusion, the perioperative mortality rate is reported to be increased by up to 39%. Malperfusion can affect many vascular beds with varying incidence and severity, resulting in coronary, cerebral, visceral, peripheral, renal or spinal malperfusion. The primary aim of this systematic review and meta-analysis is to investigate the epidemiology of specific types of organ malperfusion in acute type A aortic dissection and to analyse the impact on the survival outcomes associated with each malperfusion type.

Methods

Electronic databases PubMed, MEDLINE and Emba

SUBMITTER: Chandiramani A 

PROVIDER: S-EPMC11720173 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature