Transcriptomic Analysis of <i>Neocaridina denticulata sinensis</i> Gills Following FPPS Knockdown Reveals Its Regulatory Role in Immune Response.

ABSTRACT: Farnesyl pyrophosphate synthase (FPPS) is a key enzyme in the terpenoid biosynthesis pathway, responsible for converting isopentenyl pyrophosphate (IPP) and dimethylallyl pyrophosphate (DMAPP) into farnesyl pyrophosphate (FPP). In crustaceans, FPPS plays an important role in various physiological processes, particularly in synthesizing the crustacean-specific hormone methyl farnesoate (MF). This study analyzed the evolutionary differences in the physicochemical properties, subcellular localization, gene structure, and motif composition of FPPS in Neocaridina denticulata sinensis (named NdFPPS) compared to other species. The significant evolutionary divergence of FPPS was observed in crustaceans, likely linked to its role in MF synthesis. After the RNA interference (RNAi)-mediated kn

SUBMITTER: Li H 

PROVIDER: S-EPMC11720513 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature