BiomiX, a user-friendly bioinformatic tool for democratized analysis and integration of multiomics data.

ABSTRACT:

Background

Interpreting biological system changes requires interpreting vast amounts of multi-omics data. While user-friendly tools exist for single-omics analysis, integrating multiple omics still requires bioinformatics expertise, limiting accessibility for the broader scientific community.

Results

BiomiX tackles the bottleneck in high-throughput omics data analysis, enabling efficient and integrated analysis of multiomics data obtained from two cohorts. BiomiX incorporates diverse omics data, using DESeq2/Limma packages for transcriptomics, and quantifying metabolomics peak differences, evaluated via the Wilcoxon test with the False Discovery Rate correction. The metabolomics annotation for Liquid Chromatography-Mass Spectrometry untargeted metabolomics is additionally su

SUBMITTER: Iperi C 

PROVIDER: S-EPMC11721463 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature