Molecular epidemiology of the HIV-1 epidemic in Fiji.

ABSTRACT: Very little is known about the HIV-1 epidemic in Fiji, nor the wider South Pacific region more generally, yet new reported HIV-1 infections are on the rise. As of 2023, there are an estimated 2000 cases of HIV-1 in Fiji with heterosexual contact the primary route of transmission. In this study, we used a molecular epidemiological approach to better understand the genetic diversity of the HIV-1 epidemic in Fiji and reveal patterns of viral transmission. Between 2020 and 2021, venous blood samples were collected from people who had previously been diagnosed with HIV-1. We generated molecular data from 53 infections, representing ~2-3% of reported cases, to identify HIV-1 subtypes and determine the outbreak's trajectory. Among the 53 HIV-1 cases, we used Bayesian inference to estimate six sep

SUBMITTER: Sudhakar A 

PROVIDER: S-EPMC11721668 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature