A de novo Gene Promotes Seed Germination Under Drought Stress in Arabidopsis.

ABSTRACT: The origin of genes from noncoding sequences is a long-term and fundamental biological question. However, how de novo genes originate and integrate into the existing pathways to regulate phenotypic variations is largely unknown. Here, we selected 7 genes from 782 de novo genes for functional exploration based on transcriptional and translational evidence. Subsequently, we revealed that Sun Wu-Kong (SWK), a de novo gene that originated from a noncoding sequence in Arabidopsis thaliana, plays a role in seed germination under osmotic stress. SWK is primarily expressed in dry seed, imbibing seed and silique. SWK can be fully translated into an 8 kDa protein, which is mainly located in the nucleus. Intriguingly, SWK was integrated into an extant pathway of hydrogen peroxide content (folate synt

SUBMITTER: Jin GT 

PROVIDER: S-EPMC11721784 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature