New Pyridinium Compound from Marine Sediment-Derived Bacterium <i>Bacillus licheniformis</i> S-1.

ABSTRACT: The structural diversity of marine natural products is considered a potential resource for the pharmaceutical industry. In our study of marine-derived compounds, one bacterium Bacillus licheniformis S-1 was discovered to have the ability to produce bioactive natural products. After a further chemistry investigation, one novel 4-aminopyridinium derivative, 4-(dimethylamino)-1-(2S-((4hydroxybenzoyl)oxy)propyl)pyridin-1-ium (1), along with 15 known cyclic dipeptides (2-16) were isolated from the bacterium B. licheniformis S-1 derived from a shallow sea sediment. The structures of compounds 1-16 were elucidated through comprehensive NMR spectroscopic and specific optical rotation (OR) data analyses. Compound 6 showed antibacterial

SUBMITTER: Wang H 

PROVIDER: S-EPMC11722202 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature