Sex Differences in Gut Microbiota and Their Relation to Arterial Stiffness (MIVAS Study).

ABSTRACT:

Background

Recent research highlights the potential role of sex-specific variations in cardiovascular disease. The gut microbiome has been shown to differ between the sexes in patients with cardiovascular risk factors.

Objectives

The main objective of this study is to analyze the differences between women and men in the relationship between gut microbiota and measures of arterial stiffness.

Methods

We conducted a cross-sectional study in Spain, selecting 180 subjects (122 women, 58 men) aged between 45 and 74. Subjects with arterial stiffness were identified by the presence of at least one of the following: carotid-femoral pulse wave velocity (cf-PWV) above 12 mm/s, cardio-ankle vascular index (CAVI) above nine, or brachial-ankle pulse wave velocity (ba-PWV) above 17.

SUBMITTER: Salvado R 

PROVIDER: S-EPMC11723250 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature