Implementing novel complete blood count-derived inflammatory indices in the diabetic kidney diseases diagnostic models.

ABSTRACT:

Objectives

Hemogram inflammatory markers, including neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), red-cell distribution width (RDW), and mean platelet volume (MPV) have been associated with type 2 diabetes mellitus (T2DM) and its complications, namely diabetic kidney diseases (DKD). We aimed to develop and validate logistic regression (LR) and CatBoost diagnostic models and study the role of adding these markers to the models.

Methods

All individuals who were managed in our secondary care center from March 2020 to December 2023 were identified. After excluding the ineligible patients, train-test splitting, and data preprocessing, two baseline LR and CatBoost-based models were developed using demographic, clinical, and laboratory features. The AUC-

SUBMITTER: Hassanzadeh A 

PROVIDER: S-EPMC11723874 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature