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Molecular Characterization of Bovine Deltapapillomavirus in Equine Sarcoids in Egypt.


ABSTRACT: Bovine papillomaviruses (BPVs) commonly cause sarcoids in equines worldwide. Equine sarcoids (ESs) reduce the working ability of draft animals and produce untoward cosmetic changes in racing and dancing equine. In this study, nine horses and 16 donkeys with sarcoids were presented to Zagazig University Veterinary Clinic, Zagazig, Egypt. Of these, eight horses and six donkeys were found to be infected with BPV. On sequencing, all 14 viruses were found to be BPV1, which were distributed in two clades without specific differentiation among papillomaviruses (PVs) of donkeys, horses, and cattle. Comparison of 135 aa (319-454) of the sequenced L1 gene with reference strains revealed three conservative mutations (D346N, Q398E, and F441Y) and two nonconservative mutations (T348N and K351T). Illumi

SUBMITTER: Sobhy NM 

PROVIDER: S-EPMC11724032 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature