Attributable Risk and Consequences of Bone Mineral Density Deficits in Childhood Cancer Survivors.

ABSTRACT:

Importance

Data characterizing the severity and changing prevalence of bone mineral density (BMD) deficits and associated nonfracture consequences among childhood cancer survivors decades after treatment are lacking.

Objective

To evaluate risk for moderate and severe BMD deficits in survivors and to identify long-term consequences of BMD deficits.

Design, setting, and participants

This cohort study used cross-sectional and longitudinal data from the St Jude Lifetime (SJLIFE) cohort, a retrospectively constructed cohort with prospective follow-up. Participants in SJLIFE are adult survivors of childhood cancer who were diagnosed between 1962 and 2012 and survived 5 years or more from diagnosis. Data were collected from November 2007 to June 2020 and analyzed from Januar

SUBMITTER: Goodenough CG 

PROVIDER: S-EPMC11724346 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature