Adapting a measure of gross motor skills for individuals with CDKL5 deficiency disorder: A psychometric study.

ABSTRACT:

Purpose

Validated measures capable of demonstrating meaningful interventional change in the CDKL5 deficiency disorder (CDD) are lacking. The study objective was to modify the Rett Syndrome Gross Motor Scale (RSGMS) and evaluate its psychometric properties for individuals with CDD.

Methods

Item and scoring categories of the RSGMS were modified. Caregivers registered with the International CDKL5 Clinical Research Network uploaded motor videos filmed at home to a protected server and completed a feedback questionnaire (n = 70). Rasch (n = 137), known groups (n = 109), and intra- and inter-rater reliability analyses (n = 50) were conducted.

Results

The age of individuals with CDD ranged from 1.5 to 34.1 years. The modified scale, Gross Motor-Complex Disability (GM-CD), co

SUBMITTER: Saldaris JM 

PROVIDER: S-EPMC11725349 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature