Left ventricular hypertrophy and ventricular ectopy in mitral valve prolapse.

ABSTRACT:

Background

Sudden deaths ascribed to mitral valve prolapse (MVP) have increased ventricular mass on autopsy. It is unknown if left ventricular hypertrophy (LVH) is a risk factor for ventricular arrhythmia in MVP.

Methods

We studied all 629 patients aged 18-90 years with MVP on echocardiography between 2016 and 19 at our institution. Echocardiograms were reviewed for LVH, ventricular size and function, and valvular pathology. Complex or frequent ventricular ectopy (cfVE) was defined as ≥ 2 premature ventricular complexes (PVC) on a 10-s ECG or > 1 % PVC burden or non-sustained ventricular tachycardia on ambulatory ECG. Multivariable logistic regression and cox proportional hazards regression were used to assess the relationships between LVH, mitral valve structural features,

SUBMITTER: Cesmat AP 

PROVIDER: S-EPMC11725436 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature