Nanostructure-Mediated Photothermal Effect for Reinforcing Physical Killing Activity of Nanorod Arrays.

ABSTRACT: The physical killing of bacteria based on surface topography has attracted much attention due to the sustainable and safe prevention of biofilm formation. However, the antibacterial efficiency of biomedical implants derived solely from nanostructures or microstructures is insufficient to combat bacteria against common infections, such as methicillin-resistant Staphylococcus aureus with thick cell walls. Herein, photothermal therapy is carried out in the presence of nanorod arrays to mitigate infection of biomedical implants. Different from traditional photothermal therapy relying on a photosensitizer, the photothermal effect is mediated by light traps rendered by the nanorod arrays, and consequently, the photosensitizer is not needed. Finite element simulations and experiments are performe

SUBMITTER: Zhang G 

PROVIDER: S-EPMC11727397 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature