Genomic Investigation and Comparative Analysis of European High-Risk Clone of Acinetobacter baumannii ST2.

ABSTRACT: Multidrug-resistant Acinetobacter baumannii is a major concern in healthcare institutions worldwide. Several reports described the dissemination of A. baumannii high-risk clones that are responsible for a high number of difficult-to-treat infections. In our study, 19 multidrug-resistant A. baumannii strains from Budapest, Hungary, were investigated based on whole-genome sequencing (WGS). The obtained results were analysed together with data from 433 strains of A. baumannii from the Pathogenwatch database. WGS analysis of 19 A. baumannii strains detected that 12 belonged to ST2 and seven belonged to ST636. Among ST2 strains, 11 out of 12 carried either bla_OXA-23 or bla_OXA-58 genes; however, all strains of ST636 uniformly

SUBMITTER: Hummel D 

PROVIDER: S-EPMC11728346 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature