Evaluation of nutrient composition and bone-promoting activity of miiuy croaker (Miichthys miiuy) bone.

ABSTRACT:

Introduction

The objective of this study was to improve the economic value of the processed by-products of farmed miiuy croaker (Miichthys miiuy) by evaluating the nutrient composition and osteogenic activity of its bones. We prepared Miichthys miiuy bone peptides (MMBP) and analyzed their osteogenic potential.

Methods

We assessed the osteogenic activity of MMBP by molecular docking, MC3T3-E1 cell proliferation assay and zebrafish growth model, and evaluated its effect on osteoporosis (OP) using a retinoic acid-induced osteoporosis rat model.

Results

Sciaena ossificans bone is rich in nutrients, including 11.40% water, 59.30% ash, 1.60% crude fat, 27.10% crude protein, and 0.58% total sugars. The total amino acids account for 22.13%, including 4.3

SUBMITTER: Ouyang Q 

PROVIDER: S-EPMC11729392 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature